Conserved protein targets for developing pan-coronavirus drugs based on sequence and 3D structure similarity analyses.
Minfei MaYanqing YangLeyun WuLiping ZhouYulong ShiJiaxin HanZhijian XuWeiliang ZhuPublished in: Comput. Biol. Medicine (2022)
Keyphrases
- sequence similarity
- genome sequences
- protein structure prediction
- sequence alignment
- computational methods
- secondary structure
- protein sequences
- drug design
- drug discovery
- protein structure
- sequence data
- structural motifs
- protein folding
- contact map
- protein structural
- similarity measure
- protein families
- human genome
- amino acids
- structural properties
- pairwise