Detection of 3D atomic similarities and their use in the discrimination of small molecule protein-binding sites.
Rafael NajmanovichNatalja KurbatovaJanet M. ThorntonPublished in: ECCB (2008)
Keyphrases
- complex networks
- binding sites
- dna binding
- protein protein
- transcription factor binding sites
- sequence alignment
- drosophila melanogaster
- regulatory elements
- dna sequences
- protein interaction
- transcription factors
- gene expression
- sequence data
- similarity measure
- predicting protein
- regulatory networks
- drug discovery
- motif discovery
- biological sequences
- computational methods
- influenza virus
- feature selection
- statistical significance
- protein protein interactions
- protein sequences
- high throughput
- protein structure prediction
- protein complexes
- genome sequences
- saccharomyces cerevisiae
- protein structure