Full-length de novo protein structure determination from cryo-EM maps using deep learning.
Jiahua HeSheng-You HuangPublished in: Bioinform. (2021)
Keyphrases
- deep learning
- protein structure
- unsupervised learning
- nuclear magnetic resonance
- molecular biology
- unsupervised feature learning
- protein sequences
- expectation maximization
- protein structure prediction
- secondary structure
- mental models
- machine learning
- nmr spectra
- protein tertiary structure
- em algorithm
- weakly supervised
- amino acid sequences
- protein structure alignment
- generative model
- amino acids
- probabilistic model
- pairwise
- protein structural
- dimensionality reduction
- supervised learning
- high dimensional
- natural language
- experimentally determined
- image segmentation
- data mining