Probe-level linear model fitting and mixture modeling results in high accuracy detection of differential gene expression.
Sébastien LemieuxPublished in: BMC Bioinform. (2006)
Keyphrases
- gene expression
- model fitting
- mixture modeling
- microarray
- gene expression data
- least squares
- parameter estimation
- em algorithm
- expectation maximization
- shape model
- density estimation
- mixture model
- active appearance models
- detection algorithm
- medical image analysis
- feature selection
- computer vision
- multi objective
- image processing