Inferring new indications for approved drugs via random walk on drug-disease heterogenous networks.
Hui LiuYinglong SongJihong GuanLibo LuoZiheng ZhuangPublished in: BMC Bioinform. (2016)
Keyphrases
- random walk
- average degree
- drug design
- drug discovery
- directed graph
- markov chain
- link prediction
- transition probabilities
- network analysis
- pharmaceutical industry
- transition probability matrix
- biological networks
- stationary distribution
- markov random walk
- virtual screening
- tag ranking
- drug resistance
- graph laplacian
- community detection
- network structure
- np complete
- data sources
- pairwise