CoPhosK: A method for comprehensive kinase substrate annotation using co-phosphorylation analysis.
Marzieh AyatiDanica WiredjaDaniela SchlatzerSean MaxwellMing LiMehmet KoyutürkMark R. ChancePublished in: PLoS Comput. Biol. (2019)
Keyphrases
- preprocessing
- high accuracy
- detection method
- fully automatic
- similarity measure
- synthetic data
- classification accuracy
- computational cost
- experimental evaluation
- image analysis
- objective function
- dynamic programming
- significant improvement
- prior knowledge
- probabilistic model
- multiresolution
- feature set
- computationally efficient
- clustering method
- data analysis
- segmentation method
- high precision
- machine learning methods
- feature selection