VarBin, a novel method for classifying true and false positive variants in NGS data.
Jacob DurtschiRebecca L. MargrafEmily M. CoonrodKalyan C. MallempatiKarl V. VoelkerdingPublished in: BMC Bioinform. (2013)
Keyphrases
- synthetic data
- false positives
- data sets
- false positive rate
- test data
- input data
- noisy data
- detection method
- missing data
- statistical methods
- prior knowledge
- training samples
- training data
- clustering method
- detection rate
- missing values
- em algorithm
- computational cost
- data analysis
- data structure
- high dimensional data
- classification accuracy
- pairwise
- similarity measure