Applying Medicinal Chemistry Transformations and Multiparameter Optimization to Guide the Search for High-Quality Leads and Candidates.
Matthew D. SegallEdmund J. ChampnessChris LeedingRyan H. LilienRamgopal R. MettuBrian W. StevensPublished in: J. Chem. Inf. Model. (2011)
Keyphrases
- high quality
- search algorithm
- global search
- search strategies
- search efficiency
- search tools
- candidate solutions
- global optimization
- search space
- relational databases
- optimization algorithm
- search methods
- search strategy
- optimization problems
- image quality
- optimization process
- evolutionary algorithm
- search engine optimization
- database systems