Adaptive bi-level programming for optimal gene knockouts for targeted overproduction under phenotypic constraints.
Shaogang RenBo ZengXiaoning QianPublished in: BMC Bioinform. (2013)
Keyphrases
- bi level
- gray scale
- optimality criteria
- constraint satisfaction
- reducing the search space
- pricing model
- programming language
- adaptive threshold
- biological processes
- constrained optimization
- gene expression data
- gene expression
- optimal solution
- multiscale
- gene regulatory networks
- linear constraints
- gene ontology
- microarray
- text mining
- dynamic programming