Transmembrane topology prediction methods: A re-assessment and improvement by a consensus method using a dataset of experimentally-characterized transmembrane topology .
Masami IkedaMasafumi AraiDemelo Madrazo LaoToshio ShimizuPublished in: Silico Biol. (2001)
Keyphrases
- significant improvement
- classification method
- hybrid method
- computational cost
- alternative methods
- preprocessing
- predictive model
- statistical methods
- machine learning methods
- benchmark datasets
- benchmark data sets
- cross validation
- synthetic and real images
- test images
- prediction model
- linear regression
- synthetic data
- methods outperform
- pairwise
- topology preserving
- gold standard
- segmentation method
- missing values
- detection method
- methods require
- feature set
- support vector machine
- similarity measure
- learning algorithm
- chronological backtracking
- imputation methods
- heuristic methods
- search methods
- support vector machine svm
- high accuracy
- probabilistic model
- feature selection