APIS: accurate prediction of hot spots in protein interfaces by combining protrusion index with solvent accessibility.
Junfeng XiaXing-Ming ZhaoJiangning SongDe-Shuang HuangPublished in: BMC Bioinform. (2010)
Keyphrases
- hot spots
- solvent accessibility
- protein sequences
- secondary structure
- prediction accuracy
- protein structure
- amino acids
- location prediction
- predicting protein
- protein protein interactions
- subcellular localization
- amino acid sequences
- computational biology
- protein interaction
- protein structure prediction
- sequence databases
- high accuracy
- contact map
- index structure
- drug design
- computational methods
- protein folding
- high precision
- protein function
- sequence analysis
- key factors
- coarse grained
- molecular biology