Prediction of aptamer-protein interacting pairs using an ensemble classifier in combination with various protein sequence attributes.
Lina ZhangChengjin ZhangRui GaoRuntao YangQing SongPublished in: BMC Bioinform. (2016)
Keyphrases
- protein sequences
- ensemble classifier
- experimentally determined
- protein secondary structure
- protein secondary structure prediction
- protein structure
- protein structure prediction
- amino acids
- protein classification
- secondary structure
- remote homology detection
- protein function
- ensemble learning
- amino acid sequences
- tertiary structure
- physico chemical
- ensemble methods
- classification models
- support vector machine
- sequence analysis
- protein folding
- protein protein interactions
- random forest
- contact map
- protein protein
- pairwise
- concept drift
- amino acid composition
- multiple sequence alignments
- solvent accessibility
- predicting protein
- prediction accuracy
- fusion method
- structural motifs
- drug design
- protein complexes
- data streams
- protein interaction
- protein structural
- sequence alignment
- similarity measure