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A statistical framework for SNP calling, mutation discovery, association mapping and population genetical parameter estimation from sequencing data.
Heng Li
Published in:
Bioinform. (2011)
Keyphrases
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parameter estimation
statistical methods
statistical analysis
statistical models
maximum likelihood
genetic algorithm
experimental data
prior knowledge
least squares
em algorithm
graphical models
markov random field
probabilistic model
parameter values
random fields
parameter estimates
linkage disequilibrium