Detecting differential binding of transcription factors with ChIP-seq.
Kun LiangSündüz KelesPublished in: Bioinform. (2012)
Keyphrases
- transcription factors
- chip seq
- binding sites
- microarray
- genome wide
- gene expression
- component analysis
- dna binding
- dna sequences
- computational biology
- gene regulation
- co occurrence
- biclustering algorithms
- regulatory networks
- systems biology
- high throughput
- biomedical literature
- biological processes
- saccharomyces cerevisiae
- highly correlated
- transcription factor binding sites
- regulatory elements
- motif discovery
- statistical tests
- gene expression data
- biological networks
- statistical significance
- natural language processing
- feature space
- machine learning