Toward a generalized computational workflow for exploiting transient pockets as new targets for small molecule stabilizers: Application to the homogentisate 1, 2-dioxygenase mutants at the base of rare disease Alkaptonuria.
Andrea BerniniSilvia GalderisiOttavia SpigaGiulia BernardiniNeri NiccolaiFabrizio ManettiAnnalisa SantucciPublished in: Comput. Biol. Chem. (2017)