Network models of protein phosphorylation, acetylation, and ubiquitination connect metabolic and cell signaling pathways in lung cancer.
Karen E. RossGuolin ZhangCuneyt AkcoraYu LinBin FangJohn M. KoomenEric B. HauraMark GrimesPublished in: PLoS Comput. Biol. (2023)
Keyphrases
- signaling pathways
- lung cancer
- regulatory networks
- protein interaction networks
- protein sequences
- systems biology
- protein protein interaction networks
- functional modules
- protein protein interactions
- network structure
- gene ontology
- statistical models
- amino acids
- computational biology
- biological processes
- protein interaction
- bayesian networks
- computational models
- high throughput
- complex networks
- parameter estimation
- image registration
- high dimensional