Identification of cavities on protein surface using multiple computational approaches for drug binding site prediction.
Zengming ZhangYu LiBiaoyang LinMichael SchroederBingding HuangPublished in: Bioinform. (2011)
Keyphrases
- protein interaction
- computational approaches
- virtual screening
- protein protein interactions
- protein protein
- computational methods
- binding sites
- drug design
- protein interaction data
- protein complexes
- predicting protein
- drug discovery
- protein function
- gene expression
- protein structure
- protein function prediction
- protein sequences
- high throughput
- secondary structure
- gene ontology
- similarity searching
- computational tools
- functional modules
- machine learning
- dna binding
- high precision
- transcription factor binding sites
- data mining
- protein interaction networks
- mass spectrometry
- dna sequences
- interaction networks
- structural properties
- biomedical literature
- systems biology
- amino acids
- molecular biology
- biological systems