Quasi-Newton Stochastic Optimization Algorithm for Parameter Estimation of a Stochastic Model of the Budding Yeast Cell Cycle.
Minghan ChenBrandon D. AmosLayne T. WatsonJohn J. TysonYoung CaoClifford A. ShafferMichael W. TrossetCihan OguzGisella KakotiPublished in: IEEE ACM Trans. Comput. Biol. Bioinform. (2019)
Keyphrases
- budding yeast
- parameter estimation
- cell cycle
- systems biology
- biological processes
- experimental conditions
- maximum likelihood
- model selection
- markov random field
- least squares
- protein protein interactions
- statistical models
- em algorithm
- saccharomyces cerevisiae
- approximate inference
- expectation maximization
- high throughput
- biological data
- structure learning
- transcription factors
- image segmentation
- computational methods
- belief propagation
- biological networks
- gene expression
- regulatory networks