Kinetic and Affinity Constraints on Reactions Between Antihapten Antibodies and Nonpeptidic B-Cell Epitopes: Implications for Predicting Antibody-Mediated Modulation of Pharmacokinetics and Pharmacodynamics.
Salvador Eugenio C. CaoiliPublished in: BCB (2016)
Keyphrases
- immune response
- major histocompatibility complex
- clonal selection
- artificial immune system
- immune memory
- experimental data
- constraint programming
- constrained optimization
- global constraints
- clonal selection algorithm
- monte carlo
- constraint satisfaction
- neural network
- linear constraints
- biochemical networks
- immune cells