Combinations of Protein-Chemical Complex Structures Reveal New Targets for Established Drugs.
Olga V. KalininaOliver WichmannGordana ApicRobert B. RussellPublished in: PLoS Comput. Biol. (2011)
Keyphrases
- complex structures
- drug discovery
- virtual screening
- drug design
- chemical compounds
- similarity searching
- protein protein interactions
- high throughput
- scientific data
- chemical reactions
- binding sites
- protein structure
- ontological knowledge
- protein structure prediction
- systems biology
- data mining
- amino acids
- knowledge base
- social network analysis
- xml documents
- chemical reaction
- biological systems
- high precision