Hot spot prediction in protein-protein interactions by an ensemble system.

Quanya Liu Peng Chen Bing Wang Jun Zhang Jinyan Li

Published in: BMC Syst. Biol. (2018)

Keyphrases

hot spots
protein protein interactions
protein interaction
predicting protein
wet lab
drug design
location prediction
protein function prediction

high throughput
computational methods
network topology
experimentally determined
biomedical literature
high precision
predicting protein protein interactions
genomic data

gene ontology
systems biology
biological data
protein protein
network analysis
functional modules
protein complexes
multiple sequence alignments

biological networks
computational approaches
protein function
protein interaction data
protein interaction networks
structural properties
statistical models