Reliable scaling of position weight matrices for binding strength comparisons between transcription factors.
Xiaoyan MaDaphne EzerCarmen NavarroBoris AdryanPublished in: BMC Bioinform. (2015)
Keyphrases
- weight matrices
- dna binding
- transcription factor binding sites
- transcription factors
- weight matrix
- binding sites
- dna sequences
- gene expression
- genome wide
- microarray
- cis regulatory
- component analysis
- transcriptional regulation
- pairwise
- computational biology
- sequence data
- systems biology
- gene expression data
- saccharomyces cerevisiae
- highly correlated
- statistical tests
- co occurrence