Addressing the Challenge of Defining Valid Proteomic Biomarkers and Classifiers.
Mohammed DaknaKeith HarrisAlexandros KalousisSebastien CarpentierWalter KolchJoost P. SchanstraMarion HaubitzAntonia VlahouHarald MischakMark A. GirolamiPublished in: BMC Bioinform. (2010)
Keyphrases
- proteomic data
- ovarian cancer
- mass spectrometry
- training data
- support vector
- biomarker discovery
- svm classifier
- breast cancer
- classification models
- cancer datasets
- classification method
- machine learning methods
- supervised classification
- decision trees
- multiple classifiers
- early detection
- clinical trials
- linear classifiers
- classifier combination
- classification rate
- gene sets
- high throughput
- training samples
- mass spectrometry data
- training set
- neural network
- gastric cancer