Modeling Bi-modality Improves Characterization of Cell Cycle on Gene Expression in Single Cells.
Andrew McDavidLucas DennisPatrick DanaherGreg FinakMichael KrouseAlice WangPhilippa WebsterJoseph BeechemRaphael GottardoPublished in: PLoS Comput. Biol. (2014)
Keyphrases
- gene expression
- cell cycle
- biological processes
- expression profiles
- microarray
- transcription factors
- gene expression data
- gene expression profiles
- gene regulation
- microarray data
- saccharomyces cerevisiae
- regulatory networks
- systems biology
- high throughput
- binding sites
- biological networks
- functional modules
- biomedical literature
- gene selection
- biological data
- protein protein interactions
- dna sequences
- experimental conditions
- machine learning
- gene networks
- dimensionality reduction
- text mining
- feature selection