Disease-Associated Mutations Disrupt Functionally Important Regions of Intrinsic Protein Disorder.
Vladimir VacicPhineus R. L. MarkwickChristopher J. OldfieldXiaoyue ZhaoChad HaynesVladimir N. UverskyLilia M. IakouchevaPublished in: PLoS Comput. Biol. (2012)
Keyphrases
- geometric structure
- copy number
- transcription factor binding sites
- disordered regions
- image regions
- protein protein interaction networks
- secondary structure
- protein structure
- protein sequences
- input image
- amino acids
- global structure
- disease diagnosis
- biological entities
- sequence alignment
- protein structure prediction
- amino acid sequences
- drug design
- region of interest