Joint Bayesian inference of condition-specific miRNA and transcription factor activities from combined gene and microRNA expression data.
Benedikt ZacherKhalid AbnaofStephan GadeErfan YounesiAchim TreschHolger FröhlichPublished in: Bioinform. (2012)
Keyphrases
- bayesian inference
- binding sites
- gene expression
- gene sets
- transcription factors
- gene regulatory networks
- regulatory networks
- gene regulation
- microarray
- dna binding
- genome wide
- expression profiles
- biological processes
- probabilistic model
- gene ontology
- microarray data
- dna sequences
- cell cycle
- statistical significance
- sequence data
- transcription factor binding sites
- systems biology
- saccharomyces cerevisiae
- gene function
- gene expression data
- motif discovery
- prior information
- gene networks
- gene selection
- high throughput
- particle filter
- biological networks
- microarray data analysis
- microarray datasets
- computational biology
- protein interaction
- secondary structure
- computational methods
- interaction networks
- biomedical literature
- graphical models
- component analysis
- data sets
- bayesian networks