Sequence Alignment as Hypothesis Testing.

Lu Meng Fengzhu Sun Xuegong Zhang Michael S. Waterman

Published in: J. Comput. Biol. (2011)

Keyphrases

hypothesis testing
sequence alignment
likelihood ratio
pairwise
dynamic programming

binding sites
protein sequences
statistical tests
likelihood ratio test
hypothesis test

amino acids
robust statistical
hypothesis tests
phylogenetic analysis
null hypothesis

multiple alignment
comparative genomics
confidence intervals
machine learning