RMA with quantile normalization mixes biological signals between different sample groups in microarray data analysis.
Chang Sik KimSeungwoo HwangShu-Dong ZhangPublished in: BIBM (2014)
Keyphrases
- microarray data analysis
- microarray
- microarray data
- meaningful clusters
- biological data
- gene expression analysis
- gene expression levels
- gene expression
- high throughput
- gene expression data
- gene sets
- signal processing
- biological systems
- molecular biology
- risk management
- cluster analysis
- sample size
- differentially expressed genes
- systems biology
- highly correlated
- independent component analysis
- pairwise