Predicting disease genes based on normalized protein modules and phenotype ontology.
Jie YuanXingpeng JiangTingting HeYan WangXiyue GuoPublished in: BIBM (2015)
Keyphrases
- disease genes
- gene expression
- protein protein interaction networks
- modular ontologies
- functional modules
- protein interaction
- protein interaction networks
- biological networks
- protein structure
- genome wide
- knowledge base
- microarray
- genome wide association studies
- protein sequences
- biological processes
- protein protein interactions
- semantic relationships
- knowledge representation
- amino acids
- biological systems
- linkage disequilibrium
- data analysis
- cellular processes
- protein complexes
- information flow
- biologically meaningful
- link prediction