Characterizing the human hippocampus in aging and Alzheimer's disease using a computational atlas derived from ex vivo MRI and histology.
Daniel H. AdlerLaura E. M. WisseRanjit IttyerahJohn PlutaSong-Lin DingLong XieJiancong WangSalmon KadivarJohn L. RobinsonTheresa SchuckJohn Q. TrojanowskiMurray GrossmanJohn A. DetreMark A. ElliottJon B. ToledoWeixia LiuStephen PickupMichael I. MillerSandhitsu R. DasDavid A. WolkPaul A. YushkevichPublished in: Proc. Natl. Acad. Sci. USA (2018)
Keyphrases
- mr images
- brain structures
- magnetic resonance images
- mri data
- prostate cancer
- multiple sclerosis
- magnetic resonance
- manual segmentation
- medical images
- age related
- mouse brain
- quantitative measurements
- brain atlas
- image guided
- computational models
- mri scans
- medical image analysis
- magnetic resonance imaging
- healthy volunteers
- brain segmentation
- clinical studies
- low grade
- early diagnosis
- quantitative analysis
- shape analysis
- medical imaging
- disease progression
- brain tissue
- computer aided diagnosis
- anatomical structures
- image analysis
- brain tumors
- atlas based segmentation
- clinical applications
- probabilistic atlas
- intra subject