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Estimating the optimal threshold for a diagnostic biomarker in case of complex biomarker distributions.
Fabien Subtil
Muriel Rabilloud
Published in:
BMC Medical Informatics Decis. Mak. (2014)
Keyphrases
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gene expression data
mass spectrometry data
probability distribution
proteomic data
lung cancer
worst case
expert systems
dynamic programming
optimal solution
real world
data sets
higher level
complex systems
joint distribution
disease progression
minimum error
diagnostic tests
outcome prediction