Protein-protein interaction sites prediction by ensemble random forests with synthetic minority oversampling technique.
Xiaoying WangBin YuAnjun MaCheng ChenBingqiang LiuQin MaPublished in: Bioinform. (2019)
Keyphrases
- random forests
- protein protein interactions
- ensemble methods
- prediction accuracy
- predicting protein
- protein interaction
- random forest
- experimentally determined
- computational methods
- machine learning algorithms
- logistic regression
- tree ensembles
- decision tree ensembles
- decision trees
- high throughput
- base learners
- randomized trees
- minority class
- multiple sequence alignments
- ppi networks
- protein complexes
- ensemble learning
- biological data
- functional modules
- base classifiers
- secondary structure
- structural properties
- high precision
- data analysis
- data sets
- microarray
- gene expression
- network analysis