A cooperative strategy for parameter estimation in large scale systems biology models.
Alejandro Fernández VillaverdeJose A. EgeaJulio R. BangaPublished in: BMC Syst. Biol. (2012)
Keyphrases
- parameter estimation
- statistical models
- systems biology
- cooperative
- model selection
- maximum likelihood
- least squares
- markov random field
- em algorithm
- expectation maximization
- biological systems
- high throughput
- maximum likelihood estimation
- probabilistic model
- parameter estimation algorithm
- multi agent systems
- parameter estimates
- approximate inference
- gene regulatory networks
- biochemical networks
- structure learning
- computational models
- complex systems
- computational biology
- machine learning
- microarray