Improved Parameter Estimation for Variance-stabilizing Transformation of Gene-expression Microarray Data.
Masato InoueShin-ichi NishimuraGen HoriHiroyuki NakaharaMichiko SaitoYoshihiro YoshiharaShun-ichi AmariPublished in: J. Bioinform. Comput. Biol. (2004)
Keyphrases
- parameter estimation
- gene expression microarray data
- markov random field
- least squares
- model selection
- statistical models
- maximum likelihood
- expectation maximization
- parameter estimation algorithm
- parameter values
- em algorithm
- random fields
- approximate inference
- model fitting
- estimation problems
- posterior distribution
- maximum likelihood estimation
- parameters estimation
- feature selection
- covariance matrix
- probabilistic model