Simultaneous Genome-Wide Inference of Physical, Genetic, Regulatory, and Functional Pathway Components.
Christopher Y. ParkDavid C. HessCurtis HuttenhowerOlga G. TroyanskayaPublished in: PLoS Comput. Biol. (2010)
Keyphrases
- genome wide
- human genome
- transcription factors
- high throughput
- gene gene interactions
- complex diseases
- gene function
- dna binding
- single nucleotide polymorphisms
- association studies
- cis regulatory
- linkage disequilibrium
- regulatory networks
- genome wide association studies
- signaling pathways
- systems biology
- microarray
- gene expression
- genetic algorithm
- gene regulation
- bayesian networks
- genetic regulatory networks
- dynamic bayesian networks
- computational biology
- biological knowledge
- binding sites
- data acquisition
- high throughput sequencing