A New Approach for Parameter Estimation in the Sequence-structure Alignment of Non-coding RNAs.
Yinglei SongAlbert Y. ChiPublished in: J. Inf. Sci. Eng. (2015)
Keyphrases
- parameter estimation
- maximum likelihood
- markov random field
- least squares
- model selection
- rna sequences
- em algorithm
- expectation maximization
- multiple alignment
- parameter estimation algorithm
- random fields
- statistical models
- parameter values
- rna secondary structures
- maximum likelihood estimates
- sequence similarity
- parameters estimation
- parameter estimates
- multiple sequence alignment
- secondary structure
- model fitting
- approximate inference
- posterior distribution
- estimation problems
- background knowledge
- protein sequences
- higher order
- similarity measure