Genome-Wide Association between Transcription Factor Expression and Chromatin Accessibility Reveals Regulators of Chromatin Accessibility.
David LamparterDaniel MarbachRico RueediSven BergmannZoltán KutalikPublished in: PLoS Comput. Biol. (2017)
Keyphrases
- transcription factors
- genome wide
- differential expression
- high throughput
- transcriptional regulation
- cis regulatory
- dna binding
- binding sites
- microarray
- chip seq
- gene regulation
- human genome
- regulatory networks
- component analysis
- gene expression
- dna sequences
- gene sets
- cell cycle
- saccharomyces cerevisiae
- complex diseases
- biological processes
- computational biology
- systems biology
- highly correlated
- motif discovery
- transcription factor binding sites
- regulatory elements
- biomedical literature
- data mining
- signaling pathways
- biological data
- data processing
- machine learning