THE REAL McCOIL: A method for the concurrent estimation of the complexity of infection and SNP allele frequency for malaria parasites.
Hsiao-Han ChangColin J. WorbyAdoke YekaJoaniter NankabirwaMoses R. KamyaSarah G. StaedkeGrant DorseyMaxwell MurphyDaniel E. NeafseyAnna E. JeffreysChristina HubbartKirk A. RockettRoberto AmatoDominic KwiatkowskiCaroline O. BuckeeBryan GreenhousePublished in: PLoS Comput. Biol. (2017)
Keyphrases
- computational cost
- high accuracy
- experimental evaluation
- support vector machine
- computational complexity
- cost function
- estimation accuracy
- synthetic data
- clustering method
- pairwise
- similarity measure
- worst case
- objective function
- detection method
- machine learning methods
- monte carlo simulation
- estimation algorithm
- parametric models
- maximum likelihood estimation
- image segmentation