Generation, Validation, and Utilization of a Three-Dimensional Pharmacophore Model for EP3 Antagonists.
Rama K. MishraJasbir SinghPublished in: J. Chem. Inf. Model. (2010)
Keyphrases
- three dimensional
- input data
- prior knowledge
- mathematical model
- data mining
- object model
- similarity measure
- formal model
- objective function
- simulation model
- probabilistic model
- experimental data
- d objects
- theoretical framework
- generation process
- surface model
- database
- statistical model
- em algorithm
- probability distribution
- cost function
- bayesian networks
- high level
- clustering algorithm
- knowledge base