Supervised principal component analysis for gene set enrichment of microarray data with continuous or survival outcomes.
Xi ChenLily WangJonathan D. SmithBing ZhangPublished in: Bioinform. (2008)
Keyphrases
- microarray data
- gene sets
- principal component analysis
- gene ontology
- microarray
- biologically relevant
- feature selection
- gene selection
- biologically meaningful
- high dimensional
- gene expression
- low dimensional
- microarray data analysis
- dimensionality reduction
- data sets
- gene expression data
- microarray datasets
- biological data
- feature space
- information theoretic
- cancer classification
- cluster analysis
- high throughput
- unsupervised learning
- supervised learning
- semi supervised
- feature extraction
- statistical significance
- knowledge discovery
- informative genes
- computational methods
- fold cross validation
- support vector
- selected genes