Remote Homology Detection Using a Kernel Method that Combines Sequence and Secondary-Structure Similarity Scores.
Daniela WieserMahesan NiranjanPublished in: Silico Biol. (2009)
Keyphrases
- psi blast
- kernel methods
- secondary structure
- similarity scores
- protein classification
- remote homology detection
- similarity function
- protein sequences
- sequence analysis
- amino acids
- protein secondary structure prediction
- protein structure
- similarity measure
- tertiary structure
- rna sequences
- string kernels
- support vector
- amino acid sequences
- kernel function
- computational methods
- machine learning
- support vector machine
- structural features
- feature space
- computational biology
- similarity measurement
- statistical significance
- pairwise
- feature vectors
- protein structure prediction
- sequence alignment