LEAP: Highly accurate prediction of protein loop conformations by integrating coarse-grained sampling and optimized energy scores with all-atom refinement of backbone and side chains.
Shide LiangChi ZhangYaoqi ZhouPublished in: J. Comput. Chem. (2014)
Keyphrases
- highly accurate
- coarse grained
- protein backbone
- contact maps
- protein structure prediction
- fine grained
- low energy
- energy landscape
- protein folding
- protein structure
- protein sequences
- hiv protease
- capable of producing
- minimum energy
- accurate models
- contact map
- high quality
- high level
- amino acid sequences
- energy consumption
- high accuracy
- amino acids
- machine learning
- computational biology