Quantitative prediction model for affinity of drug-target interactions based on molecular vibrations and overall system of ligand-receptor.
Xianrui WangTing-Ting CaoCong Min JiaXuemei TianYun WangPublished in: BMC Bioinform. (2021)
Keyphrases
- prediction model
- drug discovery
- protein protein
- virtual screening
- drug design
- van der waals
- regression model
- interaction networks
- neural network
- fuzzy neural network
- protein protein interactions
- computational methods
- bp neural network
- binding sites
- molecular interactions
- response surface methodology
- high throughput
- predictive model
- wavelet neural network
- protein sequences
- customer churn
- scientific data
- software reliability
- ls svm
- living cells
- bp network
- exponential smoothing
- systems biology
- fuzzy logic
- forecasting model
- stepwise regression
- biological systems