MR-Corr2: a two-sample Mendelian randomization method that accounts for correlated horizontal pleiotropy using correlated instrumental variants.
Qing ChengTingting QiuXiaoran ChaiBaoluo SunYingcun XiaXingjie ShiJin LiuPublished in: Bioinform. (2022)
Keyphrases
- high accuracy
- experimental evaluation
- preprocessing
- computational complexity
- high precision
- objective function
- fully automatic
- detection method
- mutual information
- dynamic programming
- evolutionary algorithm
- multiresolution
- level set
- theoretical analysis
- training samples
- segmentation algorithm
- detection algorithm
- clustering method
- synthetic data
- sample size
- classification method
- training set
- neural network