State-dependent protein-lipid interactions of a pentameric ligand-gated ion channel in a neuronal membrane.
Marc A. DämgenPhilip C. BigginPublished in: PLoS Comput. Biol. (2021)
Keyphrases
- state dependent
- protein protein
- protein protein interactions
- steady state
- protein sequences
- amino acid sequences
- interaction networks
- computational methods
- drug design
- predicting protein
- protein interaction
- protein function
- high throughput
- virtual screening
- drug discovery
- optimal policy
- queueing networks
- binding sites
- protein complexes
- markov chain
- stationary distribution
- protein structure
- living cells
- single server
- arrival rate
- product form
- service rates
- asymptotically optimal
- queue length
- amino acids
- systems biology
- customer demand
- service times
- random walk
- dynamic programming