A spatio-temporal model to reveal oscillator phenotypes in molecular clocks: Parameter estimation elucidates circadian gene transcription dynamics in single-cells.
Måns UnossonMarco BrancaccioMichael HastingsAdam M. JohansenBärbel FinkenstädtPublished in: PLoS Comput. Biol. (2021)
Keyphrases
- parameter estimation
- spatio temporal
- em algorithm
- parameter values
- statistical models
- maximum likelihood
- model fitting
- statistical model
- model selection
- expectation maximization
- parameters estimation
- random fields
- experimental data
- markov random field
- least squares
- gibbs sampling
- cellular automaton
- parameter estimation algorithm
- approximate inference
- posterior distribution
- maximum entropy
- probabilistic model