MSAProbs: multiple sequence alignment based on pair hidden Markov models and partition function posterior probabilities.
Yongchao LiuBertil SchmidtDouglas L. MaskellPublished in: Bioinform. (2010)
Keyphrases
- hidden markov models
- posterior probability
- multiple sequence alignment
- bayesian networks
- bayesian framework
- probability density function
- protein sequences
- memory efficient
- probability distribution
- generative model
- computational biology
- biological sequences
- genetic algorithm
- posterior distribution
- probabilistic model
- approximate inference
- sequence alignment
- conditional probabilities
- markov networks
- pairwise
- conditional random fields
- secondary structure
- markov random field
- probabilistic inference
- closed form
- structure learning
- markov chain monte carlo
- belief propagation
- association rules
- feature selection