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Relative free-energy calculations for scaffold hopping-type transformations with an automated RE-EDS sampling procedure.

Benjamin RiesKarl NormakR. Gregor WeißSalomé RiederEmília P. BarrosCandide ChampionGerhard KönigSereina Riniker
Published in: J. Comput. Aided Mol. Des. (2022)
Keyphrases
  • free energy
  • sampling procedure
  • random sampling
  • upper bound
  • sampling algorithm
  • mean shift
  • belief propagation
  • fixed point
  • competitive learning
  • neural network