Functional analysis of microRNA and transcription factor synergistic regulatory network based on identifying regulatory motifs in non-small cell lung cancer.
Ke-ning LiZi-hui LiNing ZhaoYaoqun XuYongjing LiuYuanshuai ZhouDesi ShangFujun QiuRui ZhangZhi-qiang ChangYan XuPublished in: BMC Syst. Biol. (2013)
Keyphrases
- transcription factors
- binding sites
- lung cancer
- functional analysis
- cell cycle
- genome wide
- dna sequences
- gene expression
- gene regulation
- motif discovery
- dna binding
- component analysis
- microarray
- sequence data
- signaling pathways
- regulatory elements
- computational biology
- cancer cells
- cis regulatory
- biological processes
- regulatory networks
- statistical significance
- transcription factor binding sites
- co occurrence
- biological sequences
- cancer diagnosis
- systems biology
- saccharomyces cerevisiae
- gene sets
- transcriptional regulation
- high throughput
- highly correlated
- gene expression data
- data mining
- data sets