Contribution of Sequence Motif, Chromatin State, and DNA Structure Features to Predictive Models of Transcription Factor Binding in Yeast.
Zing Tsung-Yeh TsaiShin-Han ShiuHuai-Kuang TsaiPublished in: PLoS Comput. Biol. (2015)
Keyphrases
- transcription factors
- binding sites
- dna binding
- transcription factor binding sites
- dna sequences
- chip seq
- transcriptional regulation
- microarray
- co occurrence
- gene expression
- component analysis
- genome wide
- biological sequences
- protein families
- cis regulatory
- gene regulation
- motif discovery
- sequence data
- regulatory networks
- computational biology
- genome sequences
- saccharomyces cerevisiae
- biomedical literature
- cell cycle
- signaling pathways
- systems biology
- biological processes
- gene sets
- sequence analysis
- regulatory elements
- genomic sequences
- sequence similarity
- highly correlated
- statistical significance
- complex systems
- biological systems
- feature space
- sequence patterns
- gene expression data
- computational approaches
- protein interaction
- experimental conditions